The History of Cystic Fibrosis by Dr James Littlewood OBE

Edited and produced by Daniel Peckham



Alpha-1AT - alpha-1-antitrypsin
AAFB - alcohol and acid fast bacilli
ABPA - allergic bronchopulmonary aspergillosis
ACBT - active cycle of breathing technique
ALP - alkaline phosphatase
ALT - alanine transferase
ASL - airway surface liquid
AST - aspartate transaminase
BMD - bone mineral density
BMI - body mass index
BMC - bone mineral content                                                                                                   
BAL - bronchoalveolar lavage
CBAVD - congenital bilateral absence of the vas deferens
CFLD - cystic fibrosis liver disease                                                                                          
COPD - chronic obstructive pulmonary disease
CFTR - cystic fibrosis transmembrane conductance regulator
CFRD - cystic fibrosis related diabetes
CRP - C-reactive protein
CT - computerised tomography
DXA - dual energy X-ray absorptiometry
ECG - electrocardiogram                                                                                                     
FDA - Food ad Drug Administration
EFA - essential fatty acid                                                                                                   
ECMO - extracorporeal membrane oxygenation
eFLOW - nebuliser using mesh technology
EMLA - eutectic mixture for local anaesthetic
ESR - erythrocyte sedimentation rate
FET - forced expiratory technique
GORD - gastro-oesophageal reflux disease
GERD - gastroesophageal reflux                                                                                                HFFC - high frequency chest compression
HIVT - home intravenous antibiotic treatment
ICSI - intracytoplasmic sperm injection
Ineb - nebuliser using mesh technology
IVF - in vitro fertilisation                                                                                                           
LCI - lung clearance index
MESA - microscopic epidermal sperm aspiration
MIC - minimum inhibitory concentration
NSAID - non-steroidal anti-inflammatory drugs
PESA - percutaneous epididymal sperm aspiration                                                                   
PFT - pulmonary function test
PGD - preimplantation genetic diagnosis
Promixin - brand name for a colomycin product
QCT - quantitative computed tomography
rhDNase - recombinant human DNase (Pulmozyme)
SD - standard deviation
TNF alpha - tumour necrosis factor alpha
TIVAD - totally implantable venous access device
UDCA - ursodeoxycholic acid